Semaglutide calculator
Semaglutide is the GLP-1 agonist sold as Wegovy and Ozempic. The FDA label starts everyone at 0.25 mg once a week and steps up every 4 weeks: 0.5 mg, 1 mg, 1.7 mg, then 2.4 mg.
Semaglutide at a glance
Semaglutide units chart
5 mg vial. Rows are doses; columns show the units to draw on a U-100 syringe at each water volume.
| Dose | mL | U-100 units | Doses per vial |
|---|---|---|---|
| 100 mcg | 0.04 | 4 | 50 |
| 200 mcg | 0.08 | 8 | 25 |
| 250 mcg | 0.1 | 10 | 20 |
| 500 mcg | 0.2 | 20 | 10 |
| 1 mg | 0.4 | 40 | 5 |
| 2 mg | 0.8 | 80 | 2 |
| 2.5 mg | 1 | 100 | 2 |
| 5 mg | 2 | 200 | 1 |
Other mixes: 5 mg + 1 mL · 5 mg + 3 mL · 2 mg + 2 mL · 10 mg + 2 mL
Semaglutide questions
How many units of semaglutide should I take?
Units depend on your vial concentration, not on the drug. With a 5 mg vial reconstituted in 2 mL you have 2.5 mg/mL, so the 0.25 mg starting dose is 10 units on a U-100 insulin syringe and 1 mg is 40 units. If your vial is 10 mg in 2 mL the same 0.25 mg is 5 units. Work it out for your vial before you draw.
What is the semaglutide dosing schedule?
The FDA label is 0.25 mg weekly for weeks 1 to 4, 0.5 mg for weeks 5 to 8, 1 mg for weeks 9 to 12, 1.7 mg for weeks 13 to 16, then 2.4 mg from week 17 for Wegovy. Ozempic stops at 0.5, 1 or 2 mg. If a step is rough, the label says to hold at the current dose another 4 weeks.
How much bacteriostatic water for a 5 mg vial of Semaglutide?
Any volume the vial holds. 5 mg in 1 mL is 5 mg/mL, in 2 mL is 2.5 mg/mL and in 3 mL is 1.667 mg/mL. The water changes the units per dose, not the amount of peptide.
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