PeptideCalculations
Long-acting amylin analog · 5 mg / 10 mg vials

Cagrilintide calculator

Cagrilintide is a once-weekly amylin analog from Novo Nordisk, not yet approved. The phase 2 trial in the Lancet tested 0.3 to 4.5 mg weekly for 26 weeks and saw 6% to 10.8% weight loss.

mL
Draw to
—units
— mL on a U-100, 1 mL barrel
Concentration
—mg/mL
— mcg per unit
Doses in the vial
—
of
Cagrilintide dosage
0.3 mg to 4.5 mgper week · clinical trial (phase 2, Lau et al., Lancet 2021)
Frequency
once weekly
Timing
same day each week; if stacked with a GLP-1, most people inject both the same day
Cycle
continuous while in use; trials ran 26 and 68 weeks
Route
subcutaneous, abdomen or thigh; rotate sites
Easy mix
5 mg + 2 mL = 2.5 mg/mL, so 0.5 mg = 0.2 mL = 20 units; 0.25 mg = 10 units, 1.2 mg = 48 units, 2.4 mg = 96 units. A 10 mg vial with 4 mL gives the same numbers.

Full Cagrilintide dosage chart →

Cagrilintide units chart

5 mg vial. Rows are doses; columns show the units to draw on a U-100 syringe at each water volume.

5 mg vial + 2 mL = 2.5 mg/mL (2,500 mcg/mL, 25 mcg per unit on U-100)
DosemLU-100 unitsDoses per vial
100 mcg0.04450
200 mcg0.08825
250 mcg0.11020
500 mcg0.22010
1 mg0.4405
2 mg0.8802
2.5 mg11002
5 mg22001

Other mixes: 5 mg + 1 mL · 5 mg + 3 mL · 10 mg + 2 mL

Cagrilintide questions

How much cagrilintide should I take?

Trial doses ran 0.3 mg to 4.5 mg once weekly, and the phase 3 combination used 2.4 mg. Self-reported users start at 0.25 to 0.3 mg and double every 4 weeks or so until they reach 2.4 mg. On a 5 mg vial in 2 mL the 0.25 mg start is 10 units.

Can you take cagrilintide with semaglutide?

That pairing is CagriSema, which Novo Nordisk tested at 2.4 mg of each in REDEFINE 1 with 20.4% average weight loss at 68 weeks. In the trial both drugs were titrated together every 4 weeks. Doing it yourself with two vials has no safety data, and GI side effects were about twice as common as placebo.

How much bacteriostatic water for a 5 mg vial of Cagrilintide?

Any volume the vial holds. 5 mg in 1 mL is 5 mg/mL, in 2 mL is 2.5 mg/mL and in 3 mL is 1.667 mg/mL. The water changes the units per dose, not the amount of peptide.

Brands we recommend for Cagrilintide. We are independent and have no affiliation with any brand: no affiliate links, no referral codes, no paid placements. These are the suppliers whose testing and certificates hold up when we check them.