PeptideCalculations
gastric pentadecapeptide · studied for tendon, ligament and muscle healing, gut lining and ulcers, inflammation (animal studies)

BPC-157 dosage

BPC-157 is a 15 amino acid fragment of a stomach protein that has been studied for healing in hundreds of rat experiments, almost all from one group in Zagreb, and in almost no humans. Users most often inject 250 to 500 mcg under the skin once or twice a day for 4 to 8 weeks. Oral capsules at 500 to 1000 mcg are common for gut complaints because the peptide survives stomach acid. No human dose has ever been established.

By the Peptide Calculations editors · Updated 2026-10-19

250 mcg to 500 mcgper dose, 1 to 2 times daily

Basis: commonly reported. subcutaneous, the standard community protocol; 500 mcg twice daily is the aggressive version

How often
once or twice daily
When
any time; many split morning and evening; injection near the injured area is common but unproven
How long
4 to 8 weeks, then a break; a low 100 to 200 mcg maintenance dose is reported by some
Route
subcutaneous (abdomen, or near the injury); oral capsules for gut use
Storage
lyophilized: fridge or freezer; reconstituted: fridge, commonly used within 4 weeks (commonly reported)

Dose ranges by source

RangePerBasisNote
250 mcg to 500 mcgdose, 1 to 2 times dailycommonly reportedsubcutaneous, the standard community protocol; 500 mcg twice daily is the aggressive version
500 mcg to 1000 mcgdose, 1 to 2 times dailycommonly reportedoral, mainly for gut complaints
10 ng/kg to 10 mcg/kgdayanimal study (rats, Sikiric group)the two doses used in most rat experiments; 10 mcg/kg is about 700 mcg for a 70 kg human by simple scaling, which is not how doses translate

Titration schedule

Step up on this schedule; stay a step longer if side effects are rough.

WeeksDose
1250 mcg once daily
2-8250 to 500 mcg once or twice daily

BPC-157 dose to units chart

5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL (25 mcg per unit on a U-100 insulin syringe). 5 mg + 2 mL = 2.5 mg/mL, so 250 mcg = 0.1 mL = 10 units; 500 mcg = 20 units. A 10 mg vial with 4 mL gives the same numbers.

DosemLUnits (U-100)Doses per vial
250 mcg0.11020
300 mcg0.121216
400 mcg0.161612
450 mcg0.181811
500 mcg0.22010

Different vial or water? Full 5 mg + 2 mL table or set your own numbers below.

mL
Draw to
—units
— mL on a U-100, 1 mL barrel
Concentration
—mg/mL
— mcg per unit
Doses in the vial
—
of

Commonly stacked with

Side effects

  • injection site redness or soreness
  • nausea
  • dizziness
  • fatigue
  • headache
  • hot flushes
Before you start. Human dosing is not established. The evidence is rat studies from essentially one lab, plus a handful of small human reports, so every range here is what users say they do, not a tested dose. It is an unapproved drug, it is banned in sport, and anyone with cancer or a cancer history should be careful with any compound that drives blood vessel growth. Not medical advice; start low and talk to a clinician.

BPC-157 dosage questions

How much BPC-157 should I take?

There is no established human dose. The commonly reported range is 250 to 500 mcg injected under the skin once or twice a day for 4 to 8 weeks, which on a 5 mg vial in 2 mL is 10 to 20 units per shot. The rat studies used 10 mcg/kg, which does not convert cleanly to people.

Can you take BPC-157 orally?

Yes, and it is the one peptide where that is plausible, because it was isolated from gastric juice and is stable in stomach acid. Oral users commonly take 500 to 1000 mcg once or twice daily, mostly for gut complaints. For tendons and joints most people still inject.

How many units of BPC-157 is 250 mcg?

With 5 mg reconstituted in 2 mL you have 2500 mcg per mL, so 250 mcg is 0.1 mL, which is 10 units on a U-100 insulin syringe. With 5 mg in 1 mL it is 5 units. Check your water volume first.

Do you inject BPC-157 near the injury?

Many users do, on the theory of a local effect, and the rat studies did use local application in some models. There is no human evidence that it matters, and the peptide reaches the bloodstream either way. Abdominal subcutaneous injection is fine if the site is awkward.

How long does it take BPC-157 to work?

Users commonly report changes in soreness within 1 to 2 weeks and run cycles of 4 to 8 weeks. There are no controlled human trials, so there is no real timeline. If nothing changes after 4 weeks, more weeks are unlikely to help.

Sources

  1. Sikiric et al., Curr Pharm Des 2011, Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract (PMID 21548867)
  2. Seiwerth et al., Frontiers in Pharmacology 2021, Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
  3. Peptide Protocol Wiki, BPC-157 community protocols

Brands we recommend for BPC-157. We are independent and have no affiliation with any brand: no affiliate links, no referral codes, no paid placements. These are the suppliers whose testing and certificates hold up when we check them.

This page is an educational summary of published labels, trials and commonly reported use. It is not medical advice and does not replace a clinician.