PeptideCalculations
tripeptide antioxidant (Glu-Cys-Gly)

Glutathione dosage

Glutathione is a three-amino-acid antioxidant your cells make, sold in 200 to 1,500 mg vials. Clinic IV doses run 600 to 1,200 mg per session; the best controlled trial gave 1,400 mg IV three times a week for 4 weeks and was well tolerated with a mild, non-significant effect. Subcutaneous use is 200 to 400 mg two or three times a week. Oral glutathione is poorly absorbed, which is why people inject it.

By the Peptide Calculations editors · Updated 2026-10-19 · Studied for oxidative stress, liver support, Parkinson's symptom pilot, skin lightening (IV clinics)

Dose
1,400 mg IV three times a week
per infusion · Human trial
How often
2 to 3 times a week
any time; evening is common because some people feel sleepy after
How long
4 to 8 weeks
then reassess; clinics run ongoing weekly sessions
Route
subcutaneous
abdomen, slow push or IV in a clinic; intramuscular on the Indian label

1Dose ranges by source

RangePerBasisNote
1,400 mg IV three times a weekinfusionHuman trial
clinical trial (Hauser et al. 2009, Movement Disorders, 21 Parkinson's patients, randomized, double-blind, 4 weeks)
well tolerated, no safety concerns, no significant difference from placebo
600 mg to 1,200 mg IVinfusionCommonly reported
commonly reported
clinic drips 1 to 3 times a week; the Indian label for injectable glutathione (Maxiliv) is 300 to 600 mg daily IV or IM for liver indications
200 mg to 400 mg subcutaneousinjectionCommonly reported
commonly reported
2 to 3 times a week, 4 to 8 weeks

2Dose to units chart

600 mg vial + 3 mL bacteriostatic water = 200 mg/mL, so each unit on a U-100 insulin syringe holds 2,000 mcg.

DoseDraw (mL)UnitsDoses in vial
1,000 mg55000
1,400 mg77000
Open in the Glutathione calculatorFull 600 mg + 3 mL table

600 mg + 3 mL = 200 mg/mL, so 200 mg = 1 mL = 100 units (a full insulin syringe). 200 mg/mL is near the top of what dissolves; swirl, do not shake, and use within days because reduced glutathione oxidizes fast.

3Commonly stacked with

NAD+ · 750 mg over 6 hours IV

4Side effects

injection site stinging and swellingsulfur smell or tasteflushingnausea or crampingrare allergic reactions, more often with IV
Before you start. It is not FDA approved for injection and the IV skin-lightening use has drawn safety warnings from several regulators. Reduced glutathione oxidizes within days in solution, so old vials are mostly inactive. People with sulfite or sulfur sensitivity and asthma should be careful, since inhaled glutathione has triggered bronchospasm. Not medical advice. Talk to a clinician and start low.

Storage: lyophilized: fridge, protect from light; reconstituted: fridge, use within 3 to 7 days (commonly reported), much shorter than peptides

5Glutathione dosage questions

How much glutathione to inject subcutaneously?

200 to 400 mg two or three times a week is the common range. At 200 mg/mL that is a full 1 mL syringe per 200 mg, so split 400 mg across two sites. Push slowly; it stings.

What is the IV glutathione dose?

Clinics give 600 to 1,200 mg per drip, one to three times a week. The controlled Parkinson's pilot used 1,400 mg three times a week for 4 weeks with no safety issues. The Indian injectable label is 300 to 600 mg a day for liver indications.

How long does reconstituted glutathione last?

Days, not weeks. Reduced glutathione oxidizes once in water, faster with light and warmth. Mix what you will use within about a week, keep it cold and dark, and discard it if it turns cloudy or yellow.

Is injecting glutathione better than taking it orally?

Oral glutathione is broken down in the gut and raises blood levels little, which is the reason clinics inject it. Injection reliably raises plasma levels. Whether that changes anything you can feel is not shown in a controlled trial.

6Sources

  1. Hauser RA et al., Movement Disorders 2009, Randomized, double-blind, pilot evaluation of intravenous glutathione in Parkinson's disease (PubMed 19230029)
  2. Zuventus Healthcare, Maxiliv (glutathione 600 mg) injection product page: 300 to 600 mg daily by slow IV or IM
  3. Peptide Protocol Wiki, Glutathione 600 mg dosing calculator (community subcutaneous ranges)

Educational summary of published labels, trials and commonly reported use. Not medical advice.

Brands we recommend for GlutathioneIndependent. No affiliation with any brand, no affiliate links, no referral codes, no paid placements.
  1. 1Licensed Peptides two accredited labs on every lot, certificates public, card and Apple Pay checkout
  2. 2Core Peptides long track record, public certificates, wide catalog
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