PeptideCalculations
growth hormone secretagogue (ghrelin receptor agonist)

GHRP-6 dosage

GHRP-6 is the original growth hormone releasing peptide, shown in 1990 to release GH in healthy men at IV doses of 0.1 to 1 mcg/kg with no adverse effects in that study. It is also the hungriest of the family because it hits the ghrelin receptor hard. Users commonly inject 100 to 300 mcg under the skin two to three times daily, fasted, for 8 to 12 weeks, often timed before meals they want to eat big. It was never approved.

By the Peptide Calculations editors · Updated 2026-10-19 · Studied for growth hormone release (human studies from 1990 on), appetite, heart and tissue protection (animal studies)

Dose
0.1 mcg/kg to 1 mcg/kg
per single dose · Human trial
How often
two to three times daily
fasted: morning, post-workout and before bed; 30 minutes or more before a meal if the goal is appetite
How long
8 to 12 weeks
then 2 to 4 weeks off
Route
subcutaneous
abdomen

1Dose ranges by source

RangePerBasisNote
0.1 mcg/kg to 1 mcg/kgsingle doseHuman trial
published study (Bowers et al., JCEM 1990, 18 healthy men, IV)
dose-dependent GH release, about 7 to 70 mcg for a 70 kg adult
100 mcg to 300 mcgdose, 2 to 3 times dailyCommonly reported
commonly reported
fasted; 100 mcg is commonly called the saturation dose

2Titration schedule

Step up on this schedule. Stay a step longer if side effects are rough.

WeeksDose
1100 mcg at bedtime
2-12100 to 300 mcg, 2 to 3 times daily

3Dose to units chart

5 mg vial + 2.5 mL bacteriostatic water = 2 mg/mL, so each unit on a U-100 insulin syringe holds 20 mcg.

DoseDraw (mL)UnitsDoses in vial
0 mcg0.00010.0150000
0 mcg0.00010.0120000
1 mcg0.00030.0310000
1 mcg0.00050.055000
Open in the GHRP-6 calculatorFull 5 mg + 2.5 mL table

5 mg + 2.5 mL = 2 mg/mL, so 100 mcg = 0.05 mL = 5 units; 200 mcg = 10 units, 300 mcg = 15 units. A 10 mg vial with 5 mL gives the same 2 mg/mL.

4Commonly stacked with

CJC-1295 (no DAC) · 100 mcg to 200 mcgSermorelin · 30 mcg/kg

5Side effects

strong hunger within 20 minutescortisol increase at higher dosesprolactin increasewater retentionflushingtingling handsinjection site rednessdrowsiness
Before you start. Human dosing is not established beyond single-dose studies; the daily ranges are user protocols and there are no phase 3 trials for any use. The hunger is real and can wreck a cut, and cortisol goes up at higher doses. Avoid with active cancer or a cancer history. Not medical advice; start low and talk to a clinician.

Storage: lyophilized: fridge or freezer; reconstituted: fridge, commonly used within 4 weeks (commonly reported)

6GHRP-6 dosage questions

How much GHRP-6 should I take?

The 1990 study used 0.1 to 1 mcg/kg IV, up to about 70 mcg for a 70 kg adult. Users commonly inject 100 to 300 mcg two to three times daily, fasted. On a 5 mg vial in 2.5 mL, 100 mcg is 5 units.

Does GHRP-6 increase appetite?

Strongly. It is a ghrelin mimic and most users report intense hunger 15 to 30 minutes after a shot. People bulking time it before meals; people cutting pick ipamorelin instead.

Can I take GHRP-6 with CJC-1295?

That is the standard pairing: 100 mcg of GHRP-6 with 100 mcg of CJC-1295 no DAC in one syringe, two to three times daily, fasted. The 1990 study showed GHRP and GHRH act synergistically, which is the basis for the stack. Keep both fasted.

7Sources

  1. Bowers et al., J Clin Endocrinol Metab 1990, Growth hormone-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone (PMID 2108187)
  2. Peptide Protocol Wiki, GHRP-6 overview and protocol quick reference

Educational summary of published labels, trials and commonly reported use. Not medical advice.

Brands we recommend for GHRP-6Independent. No affiliation with any brand, no affiliate links, no referral codes, no paid placements.
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