20 mg vial + 0.5 mL bacteriostatic water
A 20 mg vial reconstituted with 0.5 mL comes to 40 mg/mL. Every unit on a U-100 insulin syringe then carries 400 mcg, so 500 mcg is 1.3 units (0.013 mL) and the vial holds 40 draws of that size.
Units for each amount
| Dose | mL | U-100 units | U-40 units | Doses per vial |
|---|---|---|---|---|
| 50 mcg | 0.0013 | 0.13 | 0.05 | 400 |
| 100 mcg | 0.0025 | 0.25 | 0.1 | 200 |
| 150 mcg | 0.0038 | 0.38 | 0.15 | 133 |
| 200 mcg | 0.005 | 0.5 | 0.2 | 100 |
| 250 mcg | 0.0063 | 0.63 | 0.25 | 80 |
| 300 mcg | 0.0075 | 0.75 | 0.3 | 66 |
| 400 mcg | 0.01 | 1 | 0.4 | 50 |
| 500 mcg | 0.013 | 1.3 | 0.5 | 40 |
| 750 mcg | 0.019 | 1.9 | 0.75 | 26 |
| 1 mg | 0.025 | 2.5 | 1 | 20 |
| 1.5 mg | 0.038 | 3.8 | 1.5 | 13 |
| 2 mg | 0.05 | 5 | 2 | 10 |
| 2.5 mg | 0.063 | 6.3 | 2.5 | 8 |
| 5 mg | 0.13 | 12.5 | 5 | 4 |
| 10 mg | 0.25 | 25 | 10 | 2 |
Same vial, other volumes
The mass does not move. Only the concentration and the unit count do.
| Water | mg/mL | mcg per unit | 500 mcg = | |
|---|---|---|---|---|
| 0.5 mL | 40 | 400 | 1.3 units | |
| 1 mL | 20 | 200 | 2.5 units | table → |
| 1.5 mL | 13.333 | 133.33 | 3.8 units | table → |
| 2 mL | 10 | 100 | 5 units | table → |
| 2.5 mL | 8 | 80 | 6.3 units | table → |
| 3 mL | 6.667 | 66.67 | 7.5 units | table → |
| 5 mL | 4 | 40 | 12.5 units | table → |
Same concentration, different vial
These pairs also come to 40 mg/mL, so their unit counts match this page exactly; only the number of draws per vial differs: 60 mg + 1.5 mL.
Try other numbers
20 mg + 0.5 mL questions
What concentration is 20 mg in 0.5 mL?
20 mg divided by 0.5 mL is 40 mg/mL, which is 40,000 mcg/mL. On a U-100 syringe each unit holds 0.01 mL, so one unit carries 400 mcg.
How many units is 500 mcg from a 20 mg vial with 0.5 mL?
500 mcg divided by 40,000 mcg/mL is 0.013 mL, which is 1.3 units on a U-100 syringe and 0.5 units on a U-40 syringe. The vial holds 40 draws of that size.
What if I add 1 mL instead of 0.5 mL to the 20 mg vial?
The mass stays 20 mg. With 1 mL the concentration is 20 mg/mL instead of 40 mg/mL, so the same amount per draw needs more units: 500 mcg becomes 2.5 units instead of 1.3.
Does a 20 mg vial hold 0.5 mL?
Usually. Most lyophilized peptide vials are 2 mL or 3 mL glass, and 0.5 mL fits with room to swirl. Check the vial if it is an unusually small format.
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