PeptideCalculations
GHRH analog, long acting

CJC-1295 (DAC) dosage

CJC-1295 with DAC is a GHRH analog that binds to albumin and lasts about 6 to 8 days, so one weekly shot raises GH and IGF-1 for the whole week. A 2006 trial in healthy adults used single doses of 30 to 60 mcg/kg, roughly 2 to 4 mg, and saw GH rise 2 to 10 times for 6 days and IGF-1 stay up for 9 to 11 days. Users commonly inject 1 to 2 mg once a week for 8 to 12 weeks. The development program was dropped and it was never approved.

By the Peptide Calculations editors · Updated 2026-10-19 · Studied for sustained growth hormone and IGF-1 elevation (phase 1 and 2 trials), body composition (user reports)

Dose
30 mcg/kg to 60 mcg/kg
per single dose · Human trial
How often
once weekly
any time; same day each week
How long
8 to 12 weeks
then a break; IGF-1 stays raised for 2 to 4 weeks after the last dose
Route
subcutaneous
abdomen

1Dose ranges by source

RangePerBasisNote
30 mcg/kg to 60 mcg/kgsingle doseHuman trial
clinical trial (phase 1, Teichman et al., JCEM 2006)
the best tolerated single doses in the trial; about 2 to 4 mg for a 70 kg adult
1 mg to 2 mgweekCommonly reported
commonly reported
once weekly, or 0.5 to 1 mg twice weekly

2Titration schedule

Step up on this schedule. Stay a step longer if side effects are rough.

WeeksDose
1-21 mg once weekly
3-121 to 2 mg once weekly

3Dose to units chart

2 mg vial + 1 mL bacteriostatic water = 2 mg/mL, so each unit on a U-100 insulin syringe holds 20 mcg.

DoseDraw (mL)UnitsDoses in vial
25 mcg0.0131.380
30 mcg0.0151.566
50 mcg0.0252.540
60 mcg0.03333
Open in the CJC-1295 (DAC) calculatorFull 2 mg + 1 mL table

2 mg + 1 mL = 2 mg/mL, so 1 mg = 0.5 mL = 50 units; 2 mg = 100 units, a full 1 mL syringe. A 5 mg vial with 2.5 mL gives the same 2 mg/mL.

4Commonly stacked with

Ipamorelin · 200 mcg to 300 mcgGHRP-2 · 1 mcg/kg

5Side effects

flushing and warmth after injectingheadachewater retentionjoint achesinjection site rednessfatiguetingling hands
Before you start. Human dosing is not established beyond a phase 1 single-dose trial, and the drug's development was discontinued. Because GH stays raised all week instead of in pulses, water retention, carpal tunnel symptoms and higher blood sugar are reported more than with the no-DAC form. Avoid with active cancer or a cancer history. Not medical advice; start low and talk to a clinician.

Storage: lyophilized: fridge or freezer; reconstituted: fridge, commonly used within 4 weeks (commonly reported)

6CJC-1295 (DAC) dosage questions

How much CJC-1295 DAC should I take per week?

The commonly reported dose is 1 to 2 mg once a week. The 2006 trial's best tolerated single doses were 30 to 60 mcg/kg, which is 2 to 4 mg for a 70 kg adult, so 2 mg sits at the low end of what was tested. On a 2 mg vial in 1 mL, 1 mg is 50 units.

How long does CJC-1295 DAC stay in your system?

The trial estimated a half-life of 5.8 to 8.1 days, with GH raised for about 6 days and IGF-1 for 9 to 11 days after one dose. After repeated weekly doses IGF-1 stayed above baseline for up to 28 days. That is why it is a once-a-week peptide.

Can I take CJC-1295 DAC with ipamorelin?

Users commonly do: the DAC version keeps baseline GH up all week and the ipamorelin adds pulses at bedtime. Doses stay the same for each, 1 to 2 mg weekly of DAC and 200 to 300 mcg of ipamorelin. Expect more water retention than either alone.

CJC-1295 DAC vs no DAC?

DAC lasts a week and raises GH continuously; no DAC lasts about 30 minutes and gives a pulse. DAC is dosed in mg once weekly; no DAC in 100 to 200 mcg doses one to three times daily. The human trial data belongs to DAC.

7Sources

  1. Teichman et al., J Clin Endocrinol Metab 2006, Prolonged stimulation of GH and IGF-I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults (PMID 16352683)
  2. Peptide Protocol Wiki, CJC-1295 DAC overview and protocol quick reference

Educational summary of published labels, trials and commonly reported use. Not medical advice.

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